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ELISpot and FluoroSpot – methods for SARS-CoV-2 vaccine development

Date:Apr 2nd, 2020 Source:Mabtech Views:638

We supply immune assays and instruments used to study immune responses, especially in vaccine development. The COVID-19 outbreak has increased the demand for several of our products, and many of our customers are currently doing research on or developing vaccines against SARS-CoV-2. We will continue to meet your urgent requests.

Products currently in high demand:

· Human and mouse interferon gamma ELISpot enable monitoring of peptide specific T-cell responses in vaccine research, e.g. used in studies of SARS-CoV-1 (Li et al, J Immunol. 2008).

· Cytokine ELISAs, ELISpot and FluoroSpot assays allow the measurement of cytokines, e.g. IL-6, GM-CSF and TNFalpha, involved in cytokine release syndrome associated with COVID-19 progression (Metha et al, Lancet 2020).

· Monoclonal antibodies against immunoglobulins, and Ig ELISpot and FluoroSpot kits aid investigations of antigen specific B-cell responses (Jahnmatz et al, J Immunol Methods 2020).

· Mabtech IRIS, our ELISpot/FluoroSpot reader facilitating unbiased spot counting, reliable multiplexing and measuring the relative spot volume.

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